Talk:Axon

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An[edit]

An automated Wikipedia link suggester has suggested 5 possible wiki links and 3 possible backlinks for the Axon article:

Notes: The article text has not been changed in any way; Some of these suggestions may be wrong, some may be right; Any edits to this page will be lost when LinkBot is next run.
Feedback: I like it, I hate it, Please don't link to — LinkBot 10:40, 17 Dec 2004 (UTC)

Outward links[edit]

I hate it

Can link cell body: ...tion potential|electrical impulses]] away from the neuron's cell body or [[neuron|soma]]. Axons are in effect the primary transmi...
Can link transmission lines: ...ll body or [[neuron|soma]]. Axons are in effect the primary transmission lines of the [[nervous system]], and as bundles they help make up...
Can link human body: ...may extend to macroscopic lengths. The longest axons in the human body, for example, are those of the [[sciatic nerve]], which run...
Can link big toe: ...h run from the base of the [[spine (anatomy)|spine]] to the big toe of each foot. These single-cell fibers may extend a metre o...
Can link electrical impulse: ...enly spaced intervals, enabling an especially rapid mode of electrical impulse propagation called [[saltatory conduction|saltation]]. ...

Inward links[edit]

Additionally, there are some other articles which may be able to linked to this one (also known as "backlinks"):

In Physicalism/Larry's text, can backlink nerve fiber: ...easure, I say? There is supposed to be a certain kind of nerve fiber that leads from your limbs to your brain, called <i>C</i>-<...
In Traumatic brain injury, can backlink nerve fiber: ...us system, consisting of a cell body (soma), a tail or long nerve fiber (axon), and projections of the cell body called dendrites. ...
In End-plate potential, can backlink nerve fibre: ...e muscle-cell membrane that lies opposite the terminal of a nerve fibre at the neuromuscular junction. The end-plate membrane is el...

An automated Wikipedia link suggester has some possible wiki link suggestions for the Axon article, and they have been placed on this page for your convenience.
Tip: Some people find it helpful if these suggestions are shown on this talk page, rather than on another page. To do this, just add {{User:LinkBot/suggestions/Axon}} to this page. — LinkBot 10:40, 17 Dec 2004 (UTC)

Expansion / wikification[edit]

I can't believe this article is so sparse! Is anyone interested in a collaboration to expand and reference this article further as it's definately close to the "bread and butter" of Neuroscience. Also, is the disambig link really neccesary? I'm quite sure that "The Claws of Axos" aren't being confused for an obscure episode of Dr Who. J O R D A N ^[talk ] 15:53, 24 January 2008 (UTC)[reply]

Passive Conduction[edit]

I'm looking for information on the passive flow of electrical current within an axon. Maybe we should consider adding a section for it. Paskari (talk) 13:01, 31 August 2008 (UTC)[reply]

Bad Picture[edit]

The picture has the word "axon" and a line pointing to the division between the first myelin sheath and the dendrite. Does anyone else think this is unclear? The word "axon" should point to the whole axon, perhaps using a curly brace, or at least point to the middle of the axon. I'll see what I can do to change it--let me know what you think. Halberdo (talk) 22:16, 15 June 2009 (UTC)[reply]

I think your change to Template:Neuron map is an improvement -- curly brackets or anything like that would probably just clutter it. Looie496 (talk) 23:15, 15 June 2009 (UTC)[reply]

Holomorphism[edit]

Hi! Is axon is holomorphic with flagellum?--MathFacts (talk) 08:40, 3 January 2010 (UTC)[reply]

No, not even homeomorphic. Looie496 (talk) 17:33, 3 January 2010 (UTC)[reply]

Do neurons have flagellae? I read that photoreceptors have flagellae through which they conduct bimpulses, but what about other neurons?--MathFacts (talk) 13:41, 25 January 2010 (UTC)[reply]

My understanding is that a flagellum is a structure that waves back and forth. I wasn't aware that photoreceptors have anything like that, and definitely most types of neurons do not. They have dendrites that can move, but more in the way that plants move than the way that animals move. Axons are like dendrites in that they grow in the same sort of way that plants do.

No I meant a structure evolved from flagellum. It has a name but I cannot remember it now.--MathFacts (talk) 01:12, 27 January 2010 (UTC)[reply]

Temperature sensitivity of afferent receptors at the ends of each fibre type[edit]

Is this worth putting in thermal thresholds, the temp. at which activity is seen in each fibre type? e.g.

A-delta type 1: 53 degreesC

A-delta type 2: 44 degreesC

C-fibres: 43 degrees C

I can find the source of this if need be. 77.184.25.39 (talk) 11:47, 17 January 2011 (UTC)[reply]

That may be a bit specific for a general article on axons. Have you thought about Thermoreceptor? --Anthonyhcole (talk) 13:08, 17 January 2011 (UTC)[reply]

Citations[edit]

Under the injury heading, I followed the link (link# 16) to the citation that was provided for the statement that concussions are a mild form of diffuse axonal damage. This citation does not suggest this to be so, and furthermore does not even mention axons. I believe the current thought is it "may" be a mild form of DAI, but even the Cleveland Clinic has given conflicting reports on this statement. — Preceding unsigned comment added by 75.144.31.134 (talk) 18:44, 20 June 2012 (UTC)[reply]

Student edits[edit]

I've seen a discussion about this page at WP:Education noticeboard, and I am now placing this page on my watchlist. If there are any student edits (or any other edits for that matter) that fail to comply with Wikipedia policies and guidelines, revert, revert, revert! And for any students or faculty members working on the page, I hope that you will read Wikipedia:Assignments for student editors. --Tryptofish (talk) 22:01, 25 March 2013 (UTC)[reply]

Orphaned references in Axon[edit]

I check pages listed in Category:Pages with incorrect ref formatting to try to fix reference errors. One of the things I do is look for content for orphaned references in wikilinked articles. I have found content for some of Axon's orphans, the problem is that I found more than one version. I can't determine which (if any) is correct for this article, so I am asking for a sentient editor to look it over and copy the correct ref content into this article.

Reference named "Daniel":

From Neural coding: Butts DA, Weng C, Jin J, et al. (September 2007). "Temporal precision in the neural code and the timescales of natural vision". Nature. 449 (7158): 92–5. Bibcode:2007Natur.449...92B. doi:10.1038/nature06105. PMID 17805296.
From Myelin: Hartline Daniel K (2008). "What is myelin?". Neuron Glia Biology. 4: 153–163. doi:10.1017/S1740925X09990263.

I apologize if any of the above are effectively identical; I am just a simple computer program, so I can't determine whether minor differences are significant or not. AnomieBOT ⚡ 16:08, 19 February 2018 (UTC)[reply]

Proposed Update of "Initial Segment"[edit]

In view of a large number of recent scientific articles about many aspects of the axon initial segment (AIS) and the giant ankyrin protein that organizes the AIS, I propose to update and expand this paragraph in hopes of providing an updated and more thorough multi-paragraph discussion. If my efforts are productive, a separate article on the AIS might be justified--too soon to know.

Comments or suggestions would be welcome.

EMIConscious (talk) 05:49, 17 June 2018 (UTC)[reply]

Right.

Here is a proposed new initial paragraph, which would precede (and require some edits in) the first sentence of the existing paragraph (footnotes to articles and links to other Wikipedia articles are shown in brackets):

"A typical neuron [link to Wikipedia article on Neuron] has an axon initial segment (AIS) that extends outward from the axon hillock [link to Wikipedia article on Axon hillock]. The AIS is different in both structure and function from other parts of the axon, and is sometimes referred to as a specialized compartment. [footnote to Leterrier et al. 2017 Frontiers in Cell Neuroscience article] One AIS function is to separate or provide a boundary between a neuron’s soma [link to Wikipedia article on Soma (biology)] or cell body and the main part of the neuron’s axon; another function is to generate and shape action potentials. [footnote to Leterrier 2018] Both of these functions support neuron cell polarity [link to Wikipedia article on Cell polarity], in which dendrites [link to Wikipedia article on Dendrite] (and, in some cases, soma) of a neuron receive input signals and the neuron’s axon provides output signals."

EMIConscious (talk) 19:33, 17 June 2018 (UTC)[reply]

Thank you for seeking input in talk before making the edit! In my opinion, that looks very good, and you should feel free to go ahead and make the edit. If there are any small tweaks that need to be made, either I or someone else will do that after. I would suggest, though, omitting the "AIS" abbreviation. --Tryptofish (talk) 19:38, 17 June 2018 (UTC)[reply]

Thanks for the input. I have discovered additional relevant literature, and am therefore reworking my edit, but intend to go ahead and make it when complete. EMIConscious (talk) 20:05, 23 June 2018 (UTC)[reply]

To Iztwoz and Tryptofish: The two of you and I have recently been editing the "Initial Segment" section of the Axon article—thanks for your contributions. As time permits, I intend to continue to edit and add material from recent scientific articles about the AIS, and perhaps you will continue to edit as well. I have a few questions/responses:

—In view of the large amount of recent scientific literature about it, do you feel that the axon initial segment deserves a Wikipedia article of its own?

—It appears that Iztwoz asked on June 24 whether there are exceptions to each axon having an initial segment; I am not aware of a case in which a stable, healthy axon lacks an initial segment, but information is scanty about initial segments in the earliest axons (perhaps in our last common ancestor with lophotrochozoans and ecdysozoans?).

—One or both of you moved some material to the “Other animals” section. In your view, is that also the appropriate place for information about evolution of the AIS throughout the bilaterians, as discussed in, e.g., Jegla et al., 2016, DOI: 10.1371.journal.pgen.1006457?

—I note that we have introduced both American and British usages. What is the usual Wikipedia practice when this occurs?—Leave as is? Change American usage to British? Or change British usage to American?

Cheers!

EMIConscious (talk) 04:53, 9 July 2018 (UTC)[reply]

It was Iztwoz who made some of those changes, and I'll defer to his answers on some of that. You are right about the WP:ENGVAR issue, and I made an edit that I think takes care of that. About most of the rest of what you ask, I think that WP:DUE becomes important here. As a result, I'm reluctant to add much of anything more to this page about the AIS. I'm not strongly opposed to separating out a standalone page about it, but I'm not really convinced that it would be sufficiently notable for that. One alternative to consider would be to add information about it to various existing pages. --Tryptofish (talk) 19:28, 9 July 2018 (UTC)[reply]

A short answer - I'm on a break at the moment - I agree with the importance of the new information and I added a summarised edit. There is more that can be said it but it seems to me that this information can be held on this page. If anything does get too big then a split can be proposed. (Also the material was moved because it was not related to studies in the human). And I need to look at the Jegla article. Thanks --Iztwoz (talk) 10:39, 10 July 2018 (UTC)[reply]

"electrical impulses known as action potentials" is wrong and must be "electrical impulses caused by action potentials", ok?[edit]

cf. "that typically conducts electrical impulses known as action potentials", has to be "that typically conducts electrical impulses caused by action potentials": a electric current = electrons moving is caused because of a difference in Voltage potential. Any objections? Sincerely, SvenAERTS (talk) 12:58, 10 February 2020 (UTC)[reply]